| SCSloan Construction:#14-closed | Duncan, SC | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| SCSloan Construction Company INC | Duncan, SC | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| SISmash Ink Design, Inc. | Spartanburg, SC | Printing and Related Support Activities323111 | — | ◇ UNVERIFIED |
| SCSouth Cooper Initiative, LLC | Inman, SC | Food Manufacturing311811 | — | ◇ UNVERIFIED |
| SCSouthland Container Corporation Dba Concept Packaging Group | Spartanburg, SC | Paper Manufacturing322211 | — | ◇ UNVERIFIED |
| SCSouthland Container Group | Spartanburg, SC | Plastics and Rubber Products Manufacturing326150 | — | ◇ UNVERIFIED |
| SISpartan Industries, INC. | Pacolet, SC | Fabricated Metal Product Manufacturing332813 | — | ◇ UNVERIFIED |
| SCSpectra Colorants INC | Union, SC | Chemical Manufacturing325132 | — | ◇ UNVERIFIED |
| STSpringfield Tool & Die, INC. | Duncan, SC | Machinery Manufacturing333515 | — | ◇ UNVERIFIED |
| SSStevenson-weir Southern - Spartanburg Plant | Wellford, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| SWStowe Woodward INC Xerium INC | Spartanburg, SC | Textile Mills313310 | — | ◇ UNVERIFIED |
| STSuminoe Textiles of America | Cowpens, SC | Apparel Manufacturing315999 | — | ◇ UNVERIFIED |
| TEThe Esab Group INC | Union, SC | Primary Metal Manufacturing331491 | — | ◇ UNVERIFIED |
| TCThomas Concrete Cowpens | Cowpens, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| TCThomas Concrete of South Carolina INC - Spartanburg New Cut | Spartanburg, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| TCThomas Concrete of South Carolina Upstate Portable Plant 01 | Spartanburg, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| TCTimken Company - Tyger River | Union, SC | Fabricated Metal Product Manufacturing332991 | — | ◇ UNVERIFIED |
| TMTns Mills:spartanburg-closed | Spartanburg, SC | Textile Mills313210 | — | ◇ UNVERIFIED |
| TPToptec Products LLC | Moore, SC | Textile Product Mills314912 | — | ◇ UNVERIFIED |
| TCToray Composite Materials America INC | Moore, SC | Chemical Manufacturing325220 | — | ◇ UNVERIFIED |
| UTUnited Tool & Mold INC | Duncan, SC | Machinery Manufacturing333511 | — | ◇ UNVERIFIED |
| VTVan Trust Portable | Roebuck, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| WAWear Active LLC | Inman, SC | Textile Product Mills314999 | — | ◇ UNVERIFIED |
| WPWilson Property Holdings LLC | Duncan, SC | Chemical Manufacturing325180 | — | ◇ UNVERIFIED |
| WMWyoming Machine, LLC | Duncan, SC | Machinery Manufacturing333519 | — | ◇ UNVERIFIED |
