| GLGreat Lakes Cheese of La Crosse, Wisconsin, INC. | La Crosse | WI | Food Manufacturing311513 | 100-499 | ◐ LIKELY ACTIVE |
| TCTorrance Casting INC | La Crosse | WI | Primary Metal Manufacturing331510 | 20-99 | ◐ LIKELY ACTIVE |
| CCC & C Machine INC. | La Crosse | WI | Fabricated Metal Product Manufacturing332710 | — | ◐ LIKELY ACTIVE |
| FIFiberpro INC Dba Advanced Fiber Products | La Crosse | WI | Plastics and Rubber Products Manufacturing326120 | — | ◐ LIKELY ACTIVE |
| MIMidwest Industrial Fuel INC | La Crosse | WI | Petroleum and Coal Products Manufacturing324121 | 1-19 | ◐ LIKELY ACTIVE |
| CBCrown Beverage Packaging | La Crosse | WI | Fabricated Metal Product Manufacturing332119 | — | ◐ LIKELY ACTIVE |
| BSBakalars Sausage Co., Inc. | La Crosse | WI | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| ILInland Label and Marketing Services, LLC - Airport Road | La Crosse | WI | Printing and Related Support Activities323110 | 100-499 | ◐ LIKELY ACTIVE |
| ILInland Label and Marketing Services, LLC - Breezy Point | La Crosse | WI | Printing and Related Support Activities323110 | 20-99 | ◐ LIKELY ACTIVE |
| ILInland Label and Marketing Services, LLC - West Ave | La Crosse | WI | Printing and Related Support Activities323110 | 20-99 | ◐ LIKELY ACTIVE |
| KTKwik Trip Dairy 769 | La Crosse | WI | Food Manufacturing311511 | 100-499 | ◐ LIKELY ACTIVE |
| KTKwik Trip Sweet Goods Bakery 779 | La Crosse | WI | Food Manufacturing311811 | 100-499 | ◐ LIKELY ACTIVE |
| MMMcloone Metal Graphics INC | La Crosse | WI | Printing and Related Support Activities323110 | — | ◐ LIKELY ACTIVE |
| MMMidwest Millwork & Casework LLC | La Crosse | WI | Furniture and Related Product Manufacturing337212 | 20-99 | ◐ LIKELY ACTIVE |
| WIWalzcraft Industries INC | La Crosse | WI | Wood Product Manufacturing321911 | 100-499 | ◐ LIKELY ACTIVE |
| CIChart Industries - La Crosse, WI | La Crosse | WI | Fabricated Metal Product Manufacturing332410 | 100-499 | ◐ LIKELY ACTIVE |
| CHCommercial HVAC - Americas : MFG-La Crosse, WI-USA | La Crosse | WI | Machinery Manufacturing333415 | 500+ | ◐ LIKELY ACTIVE |
| DLDbm LLC | La Crosse | WI | Miscellaneous Manufacturing339113 | — | ◐ LIKELY ACTIVE |
| DVDna Vintners | La Crosse | WI | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| EVEngstrom Vineyards | La Crosse | WI | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| KTKwik Trip Bread and Bun Bakery 979 | La Crosse | WI | Food Manufacturing311812 | 100-499 | ◐ LIKELY ACTIVE |
| MWMom Water | La Crosse | WI | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| PSPearl Street Cidery | La Crosse | WI | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| PPPowered Printing | La Crosse | WI | Printing and Related Support Activities323111 | 1-19 | ◐ LIKELY ACTIVE |
| RSRed State Spirits | La Crosse | WI | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| RORosemont of Virginia, LLC | La Crosse | VA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| SCSelect Custom Solutions | La Crosse | WI | Food Manufacturing311514 | 100-499 | ◐ LIKELY ACTIVE |
| SStampline | La Crosse | WI | Machinery Manufacturing333514 | 20-99 | ◐ LIKELY ACTIVE |
| SSSteiger Steel & Fabricating | La Crosse | WI | Primary Metal Manufacturing331110 | 1-19 | ◐ LIKELY ACTIVE |
| TLThe Long Drink Company | La Crosse | WI | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| VVirginia | La Crosse | VA | Furniture and Related Product Manufacturing337920 | 100-499 | ◐ LIKELY ACTIVE |