Daktronics, INC. | Brookings | — | ● ACTIVE |
Gopher Sign CO | Clear Lake | — | ● ACTIVE |
Mastel Precision Surgical Instruments, INC. | Rapid City | — | ● ACTIVE |
Midwest Eye Laboratories Sioux Falls, LLC | Sioux Falls | — | ● ACTIVE |
Esco Mfg., INC. | Watertown | — | ● ACTIVE |
Hanger Prosthetics & Orthotics East INC | Dakota Dunes | — | ● ACTIVE |
Hanger Prosthetics & Orthotics East, INC. | Rapid City | — | ● ACTIVE |
Kna Custom Creations, LLC | Sioux Falls | — | ● ACTIVE |
| PNPride Neon INC | Sioux Falls | 20–99 | ● ACTIVE |
Ramvac Dental Products, INC | Spearfish | — | ● ACTIVE |
Rosenbaum's Signs & Outdoor Advertising, INC. | Rapid City | — | ● ACTIVE |
Shooter First LLC | Sioux Falls | — | ● ACTIVE |
| CSCreative Surfaces INC | Sioux Falls | 100–499 | ◐ LIKELY ACTIVE |
| DIDaktronics Incorporated | Brookings | — | ◐ LIKELY ACTIVE |
Daktronics, INC. | Sioux Falls | — | ◇ UNVERIFIED |
| MMMitchell Manufacturing, LLC | Mitchell | — | ◇ UNVERIFIED |
| MMMajestic Medical LLC | Harrisburg | — | ◐ LIKELY ACTIVE |
| UIUltiMed Inc. | De Smet | 20–99 | ◐ LIKELY ACTIVE |
| PIPersona INC. - Watertown | Watertown | — | ◐ LIKELY ACTIVE |
| CRChicago Rawhide Manufacturing Company | Springfield | — | ◇ UNVERIFIED |
| CCColeman CO | Rapid City | — | ◇ UNVERIFIED |
| EMEsco Manufacturing, INC. | Watertown | — | ◇ UNVERIFIED |
| HSHfw Solutions | Rapid City | — | ◇ UNVERIFIED |
| RGRiddles Group, INC. | Rapid City | — | ◇ UNVERIFIED |
| WMWheeler Manufacturing Co, INC. | Lemmon | — | ◇ UNVERIFIED |
| B4Branch 418 | Sioux Falls | 1–19 | ◐ LIKELY ACTIVE |
| BBrookings-3mus-sd | Brookings | 1–19 | ◐ LIKELY ACTIVE |
| BPBrookings-sd-falcon Plastics | Brookings | 1–19 | ◐ LIKELY ACTIVE |
| BWBrookings - Warehouse 1 | Brookings | 1–19 | ◐ LIKELY ACTIVE |
| BWBrookings - Warehouse 2 | Brookings | 1–19 | ◐ LIKELY ACTIVE |
| BWBrookings - Warehouse 3 | Brookings | 1–19 | ◐ LIKELY ACTIVE |
| ITImmutrix Therapeutics, INC. | Rapid City | — | ◐ LIKELY ACTIVE |
| LELakota Enterprises INC | Rapid City | — | ◐ LIKELY ACTIVE |
| NLNevr Looz LLC | Sioux Falls | — | ◐ LIKELY ACTIVE |
| PDProSmiles Dental Studio | Rapid City | 20–99 | ◐ LIKELY ACTIVE |
| PDProSmiles Dental Studio Sioux Falls | Sioux Falls | 1–19 | ◐ LIKELY ACTIVE |
| PRProsperous Robotics Group, INC. | Sioux Falls | — | ◐ LIKELY ACTIVE |
| RPRainbow Play Systems, Inc. | Brookings | 20–99 | ◐ LIKELY ACTIVE |
| RDRegional Dental Lab, LLC | Sioux Falls | — | ◐ LIKELY ACTIVE |
| SDSd01-dakt-south Dakota Brookings | Brookings | 500+ | ◐ LIKELY ACTIVE |
| SDSd02-dakt-south Dakota Sioux Falls | Sioux Falls | 100–499 | ◐ LIKELY ACTIVE |
| SDSouth Dakota | Brandon | 1–19 | ◐ LIKELY ACTIVE |
| WPWells Plumbing LLC | Belle Fourche | — | ◐ LIKELY ACTIVE |
| ASAce Sign Displays, INC. | Dakota Dunes | — | ◇ UNVERIFIED |
| AHAiden Holdings LLC | Rapid City | — | ◇ UNVERIFIED |
| AEApex Electric & Sign LLC | Rapid City | — | ◇ UNVERIFIED |
| BMB &B Molding Inc | Brandon | — | ◇ UNVERIFIED |
| BSBruce Sign Company | Sioux Falls | — | ◇ UNVERIFIED |
| GFG3 Fire, LLC | Sioux Falls | — | ◇ UNVERIFIED |
| JSJewelryMonk Studio and Training Center Jewelry by DeCory | Rapid City | — | ◇ UNVERIFIED |