| CMCoopervision Manufacturing Puerto Rico LLC | Juana Diaz, PR | Miscellaneous Manufacturing339115 | 500+ | ● ACTIVE |
| DSDestileria Serralles INC | Ponce, PR | Beverage and Tobacco Product Manufacturing312140 | — | ● ACTIVE |
Nutrition Group LLC | Ponce, PR | Food Manufacturing311942 | — | ● ACTIVE |
| ZMZimmer Manufacturing B.v. | Mercedita, PR | Miscellaneous Manufacturing339113 | — | ◐ LIKELY ACTIVE |
| PCPonce Can | Ponce, PR | Food Manufacturing311821 | 1–19 | ◐ LIKELY ACTIVE |
| POPeerless Oil & Chemicals, INC - Penuelas | Penuelas, PR | Petroleum and Coal Products Manufacturing324110 | — | ◐ LIKELY ACTIVE |
| SSSartorius Stedim Filters, INC | Bda Lluberas, PR | Plastics and Rubber Products Manufacturing326111 | — | ◐ LIKELY ACTIVE |
| MPMaster Paints & Chemical Corporation | Guayanilla, PR | Chemical Manufacturing325510 | — | ◐ LIKELY ACTIVE |
| CDCemex De Puerto Rico, INC. | Ponce, PR | Nonmetallic Mineral Product Manufacturing327310 | — | ◐ LIKELY ACTIVE |
| DTDemaco Terminal Operations CORP | Guayanilla, PR | Plastics and Rubber Products Manufacturing326111 | — | ◐ LIKELY ACTIVE |
| ADAsfalto Del Oeste | Guayanilla, PR | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| BLBilchem LTD | Ponce, PR | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| BPBrake Parts Puerto Rico INC | Ponce, PR | Plastics and Rubber Products Manufacturing326291 | — | ◇ UNVERIFIED |
| CCCheckpoint Caribbean LTD | Ponce, PR | Computer and Electronic Product Manufacturing334419 | — | ◇ UNVERIFIED |
| EIEssilor Industries | Ponce, PR | Miscellaneous Manufacturing339115 | — | ◇ UNVERIFIED |
| GCGulf Chemical CORP. | Penuelas, PR | Petroleum and Coal Products Manufacturing324110 | — | ◇ UNVERIFIED |
| MPMaster Paints & Chemicals CORP | Guayanilla, PR | Chemical Manufacturing325510 | — | ◇ UNVERIFIED |
| PPPlanta Peñuelas | Peñuelas, PR | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| PCPonce Concrete Blk 1 | Ponce, PR | Nonmetallic Mineral Product Manufacturing327331 | — | ◇ UNVERIFIED |
| PDProductos De Agregados - Cantera Naranjo | Juana Diaz, PR | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| PRPuerto Rico Terminals Group, LLC | Penuelas, PR | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| SWSouthern Wood Treating, INC. | Guayanilla, PR | Wood Product Manufacturing321114 | — | ◇ UNVERIFIED |
| CLCds LLC | Ponce, PR | Furniture and Related Product Manufacturing337110 | — | ◐ LIKELY ACTIVE |
| CRColon Raffucci Carlos F | Ponce, PR | Food Manufacturing311812 | — | ◐ LIKELY ACTIVE |
| GSGanaderia Santiago Inc. | Yauco, PR | Food Manufacturing311611 | — | ◐ LIKELY ACTIVE |
| HSHermanos Santiago Cash & Carry | Ponce, PR | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| JPJM Packing | Ponce, PR | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| KCKrly's Cabinetry Design LLC | Ponce, PR | Furniture and Related Product Manufacturing337127 | — | ◐ LIKELY ACTIVE |
| MPManhattan Packing, Inc. | Ponce, PR | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| RFR & F Asphalt Unlimited INC | Coto Laurel, PR | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| RBRovira Biscuit Corporation | Ponce, PR | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| SGSangria Giorgio | Ponce, PR | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| SGSangria Giorgio LLC | Ponce, PR | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| SPSangria Para Maestras | Ponce, PR | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| WCWilfredo Cornier | Ponce, PR | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| ICIndustrial Chemicals Corporation | Penuelas, PR | Chemical Manufacturing325180 | — | ◇ UNVERIFIED |
| AAAmilcar Arroyo Santiago | Ponce, PR | Food Manufacturing311812 | — | ◇ UNVERIFIED |
| APAtlantic Pipe CORP | Juana Diaz, PR | Nonmetallic Mineral Product Manufacturing327332 | — | ◇ UNVERIFIED |
| BABetteroads Asphalt Plt Ponce | Ponce, PR | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| CSCancel Services CORP | Ponce, PR | Primary Metal Manufacturing331315 | — | ◇ UNVERIFIED |
| CCCoopervision Caribbean Corporation | Juana Diaz, PR | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| CMCoopervision Manufacturing Puerto Rico LLC | Juana Diaz, PR | Miscellaneous Manufacturing339115 | — | ◇ UNVERIFIED |
| DJDon Julio Tropical Food LLC | Ponce, PR | Food Manufacturing311942 | — | ◇ UNVERIFIED |
| LHLa Hielera, INC. | Ponce, PR | Beverage and Tobacco Product Manufacturing312113 | — | ◇ UNVERIFIED |
| LGLinde Gas Puerto Rico INC | Guayanilla, PR | Chemical Manufacturing325120 | — | ◇ UNVERIFIED |
| MPMedtronic Pr Operation Company | Villalba, PR | Computer and Electronic Product Manufacturing334510 | — | ◇ UNVERIFIED |
| PIPanaderia Imperial | Ponce, PR | Food Manufacturing311812 | — | ◇ UNVERIFIED |
| PMPepsicola Mfg Intl | Ponce, PR | Beverage and Tobacco Product Manufacturing312111 | — | ◇ UNVERIFIED |
| PBPonce Bicycle Supply CORP. (los Pedales) | Ponce, PR | Transportation Equipment Manufacturing336991 | — | ◇ UNVERIFIED |
| PRPonce Rubber Rollers INC | Ponce, PR | Chemical Manufacturing325212 | — | ◇ UNVERIFIED |