 Pmb INC | Poplar Bluff, MO | Plastics and Rubber Products Manufacturing326199 | 1–19 | ● ACTIVE |
 Bluff Prosthetics and Orthotics, LLC | Poplar Bluff, MO | Miscellaneous Manufacturing339113 | — | ● ACTIVE |
 Hanger Prosthetics & Orthotics East, INC. | Poplar Bluff, MO | Miscellaneous Manufacturing339113 | — | ● ACTIVE |
 Ideal Medical Products, INC. | Broseley, MO | Fabricated Metal Product Manufacturing332322 | — | ● ACTIVE |
| RIRobertson, Incorporated Bridge and Grading Division | Poplar Bluff, MO | Petroleum and Coal Products Manufacturing324121 | — | ● ACTIVE |
| GCGates Corporation Poplar Bluff Division | Poplar Bluff, MO | Textile Mills313320 | — | ◐ LIKELY ACTIVE |
| RFRowe Furniture Corp-poplar Bluff | Poplar Bluff, MO | Furniture and Related Product Manufacturing337121 | — | ◇ UNVERIFIED |
| BCBates County Redi-mix INC - Butler Plant | Butler, MO | Nonmetallic Mineral Product Manufacturing327320 | — | ◐ LIKELY ACTIVE |
| SPScott Post Company | Poplar Bluff, MO | Wood Product Manufacturing321114 | — | ◐ LIKELY ACTIVE |
| TATrans a Matic INC | Poplar Bluff, MO | Fabricated Metal Product Manufacturing332999 | — | ◐ LIKELY ACTIVE |
| DADavid Arndt's Cabinets | Poplar Bluff, MO | Furniture and Related Product Manufacturing337110 | — | ◇ UNVERIFIED |
| ESEssex Specialty Prods INC | Poplar Bluff, MO | Chemical Manufacturing325520 | — | ◇ UNVERIFIED |
| GRGates Rubber-refurbishing | Poplar Bluff, MO | Textile Mills313320 | — | ◇ UNVERIFIED |
| NGNortek Global Hvac | Poplar Bluff, MO | Machinery Manufacturing333415 | — | ◇ UNVERIFIED |
| PBPoplar Bluff Plant | Poplar Bluff, MO | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| RPRevere Plastics Systems | Poplar Bluff, MO | Textile Mills313320 | — | ◇ UNVERIFIED |
| SHSchaller Hardwood Lumber Co-yard 2 | Poplar Bluff, MO | Wood Product Manufacturing321113 | — | ◇ UNVERIFIED |
| SHSpencer's Hwy 53 Ready Mix | Poplar Bluff, MO | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| SUStarting USA | Poplar Bluff, MO | Fabricated Metal Product Manufacturing332117 | — | ◇ UNVERIFIED |
| BOBronze Owl Brewing | Poplar Bluff, MO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| EPEagle Pass winery | Poplar Bluff, MO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| ICIndian Creek Meats | Poplar Bluff, MO | Food Manufacturing311611 | — | ◐ LIKELY ACTIVE |
| KDKing David's Winery LLC | Poplar Bluff, MO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| MPMo-Ark Provision Company Inc | Poplar Bluff, MO | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| PBPoplar Bluff | Poplar Bluff, MO | Beverage and Tobacco Product Manufacturing312111 | 20–99 | ◐ LIKELY ACTIVE |
| WTWilder Trading L.l.c | Poplar Bluff, MO | Apparel Manufacturing315990 | — | ◐ LIKELY ACTIVE |
| BSBootheel Sign Company | Poplar Bluff, MO | Miscellaneous Manufacturing339950 | — | ◇ UNVERIFIED |
| BSBriggs & Stratton Corporation | Poplar Bluff, MO | Machinery Manufacturing333618 | — | ◇ UNVERIFIED |
| CCCane Creek Mills INC. | Poplar Bluff, MO | Wood Product Manufacturing321920 | — | ◇ UNVERIFIED |
| FBFlowers Baking Company, INC. | Poplar Bluff, MO | Food Manufacturing311812 | — | ◇ UNVERIFIED |
| FPFortis Plastics | Poplar Bluff, MO | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| IPIdeal Products | Broseley, MO | Miscellaneous Manufacturing339112 | — | ◇ UNVERIFIED |
| MCMid Continent Steel & Wire, INC. | Poplar Bluff, MO | Primary Metal Manufacturing331222 | — | ◇ UNVERIFIED |
| PDPorter Dewitt Ready Mix Co-south Plant | Poplar Bluff, MO | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| RTRice Trailers | Harviell, MO | Machinery Manufacturing333924 | — | ◇ UNVERIFIED |
| RTRice Trailers, INC. | Harviell, MO | Transportation Equipment Manufacturing336214 | — | ◇ UNVERIFIED |
| RWRick's Woodworking & Custom Cabinets | Poplar Bluff, MO | Furniture and Related Product Manufacturing337110 | — | ◇ UNVERIFIED |
| SRSemo Ready Mix - Poplar Bluff North | Poplar Bluff, MO | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| SRSemo Ready Mix - Poplar Bluff South | Poplar Bluff, MO | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| SRStar Ready Mix INC. | Poplar Bluff, MO | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| TTT & T Mfg | Fisk, MO | Fabricated Metal Product Manufacturing332111 | — | ◇ UNVERIFIED |
