Porter Industries LLC | Franklin Furnace, OH | Fabricated Metal Product Manufacturing332999 | — | ● ACTIVE |
| EFEvans Food Group, LTD | Portsmouth, OH | Food Manufacturing311612 | 100–499 | ● ACTIVE |
Hanger Prosthetics & Orthotics, INC. | Portsmouth, OH | Miscellaneous Manufacturing339113 | — | ● ACTIVE |
Yost Labs INC. | Portsmouth, OH | Computer and Electronic Product Manufacturing334511 | — | ● ACTIVE |
| AWAppalachian Wood Floors, INC | Portsmouth, OH | Wood Product Manufacturing321114 | 100–499 | ◐ LIKELY ACTIVE |
| HNHaverhill North Cogeneration Facility | Franklin Furnace, OH | Petroleum and Coal Products Manufacturing324199 | — | ◐ LIKELY ACTIVE |
| OIOsco Industries INC Portsmouth Div | Portsmouth, OH | Primary Metal Manufacturing331511 | — | ◐ LIKELY ACTIVE |
| OIOsco Industries, INC. New Boston Divisi (0773010180) | New Boston, OH | Primary Metal Manufacturing331511 | — | ◇ UNVERIFIED |
| AMA & M Refractories, INC. | New Boston, OH | Nonmetallic Mineral Product Manufacturing327120 | 20–99 | ◐ LIKELY ACTIVE |
| VKVinyl Kraft Acquisition | New Boston, OH | Fabricated Metal Product Manufacturing332321 | 100–499 | ◐ LIKELY ACTIVE |
| KHKelsey Hayes Landfill | Portsmouth, OH | Transportation Equipment Manufacturing336000 | — | ◐ LIKELY ACTIVE |
| SCSole Choice, INC. (0773010234) | Portsmouth, OH | Textile Mills313220 | — | ◐ LIKELY ACTIVE |
| NBNew Boston Coke CORP | New Boston, OH | Primary Metal Manufacturing331110 | — | ◇ UNVERIFIED |
| SCSole Choice, INC. (0773010120) | Portsmouth, OH | Textile Mills313220 | — | ◇ UNVERIFIED |
| VAValley Asphalt #24 | Lucasville, OH | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| GJG J Pepsi- Cola -Franklin Furnace OH | Franklin Furnace, OH | Beverage and Tobacco Product Manufacturing312111 | 100–499 | ◐ LIKELY ACTIVE |
| NBNew Boston Division | New Boston, OH | Primary Metal Manufacturing331511 | 20–99 | ◐ LIKELY ACTIVE |
| PDPortsmouth Division | Portsmouth, OH | Primary Metal Manufacturing331511 | 100–499 | ◐ LIKELY ACTIVE |
| SCSole Choice, Inc | Portsmouth, OH | Textile Mills313220 | 20–99 | ◐ LIKELY ACTIVE |
| SBSpeyside Bourbon Stave Mill in McDermott Ohio, Inc. | Mc Dermott, OH | Wood Product Manufacturing321113 | 20–99 | ◐ LIKELY ACTIVE |
| SESunCoke Energy Haverhill Operations | Franklin Furnace, OH | Petroleum and Coal Products Manufacturing324199 | 100–499 | ◐ LIKELY ACTIVE |
| SASweet As Sin, LLC | Lucasville, OH | Food Manufacturing311821 | — | ◐ LIKELY ACTIVE |
| TPThe Portsmouth Brewing Company | Portsmouth, OH | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| TCTri-America Contractors Inc | Wheelersburg, OH | Fabricated Metal Product Manufacturing332996 | 20–99 | ◐ LIKELY ACTIVE |
| WMWB Metals LLC | Lucasville, OH | Fabricated Metal Product Manufacturing332710 | 20–99 | ◐ LIKELY ACTIVE |
| TLTaylor Lumber Worldwide, INC. | Mc Dermott, OH | Wood Product Manufacturing321113 | — | ◇ UNVERIFIED |
| AWAppalachian Wood Floors, INC. | Portsmouth, OH | Wood Product Manufacturing321918 | — | ◇ UNVERIFIED |
| CCinao | Franklin Furnace, OH | Petroleum and Coal Products Manufacturing324199 | — | ◇ UNVERIFIED |
| CCinao | Franklin Furnace, OH | Beverage and Tobacco Product Manufacturing312111 | — | ◇ UNVERIFIED |
| CACunningham Asphalt Paving INC. (0773000034) | Wheelersburg, OH | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| GJG & J Pepsi Cola Bottlers, INC. | Franklin Furnace, OH | Beverage and Tobacco Product Manufacturing312111 | — | ◇ UNVERIFIED |
| HCHaverhill Chemicals LLC | Haverhill, OH | Petroleum and Coal Products Manufacturing324199 | — | ◇ UNVERIFIED |
| SMShelly Materials Plant 47 (0773000237) | Lucasville, OH | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| SESuncoke Energy | Franklin Furnace, OH | Petroleum and Coal Products Manufacturing324199 | — | ◇ UNVERIFIED |
| TBThe Briar Hill Stone Company | Mc Dermott, OH | Nonmetallic Mineral Product Manufacturing327991 | — | ◇ UNVERIFIED |