| PIPolaris Industries, INC - Spirit Lake | Spirit Lake, IA | Transportation Equipment Manufacturing336991 | 100–499 | ● ACTIVE |
 Brownmed, Inc. | Spirit Lake, IA | Miscellaneous Manufacturing339113 | 20–99 | ● ACTIVE |
| PMPFG Manufacturing OLM Food Systems Milford IA - 4042 | Milford, IA | Food Manufacturing311612 | 20–99 | ● ACTIVE |
| GPGreen Plains Superior LLC | Superior, IA | Chemical Manufacturing325193 | 20–99 | ◐ LIKELY ACTIVE |
 Rosenboom Machine & Tool Inc-spirit Lake | Spirit Lake, IA | Machinery Manufacturing333995 | — | ◇ UNVERIFIED |
| HTH T C INC | Milford, IA | Machinery Manufacturing333922 | — | ◇ UNVERIFIED |
| PFPure Fishing Incorporated | Spirit Lake, IA | Miscellaneous Manufacturing339920 | — | ◇ UNVERIFIED |
| RMRosenboom Machine & Tool, INC. | Spirit Lake, IA | Machinery Manufacturing333995 | — | ◇ UNVERIFIED |
| SIStylecraft INC | Milford, IA | Furniture and Related Product Manufacturing337121 | — | ◇ UNVERIFIED |
| IIIntercept Industries, Ltd | Spirit Lake, IA | Transportation Equipment Manufacturing336390 | 1–19 | ◐ LIKELY ACTIVE |
| LSLittle Swan Lake Winery | Estherville, IA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
 Safco Products - Milford, IA | Milford, IA | Furniture and Related Product Manufacturing337214 | 20–99 | ◐ LIKELY ACTIVE |
| SLSpirit Lake Branch | Spirit Lake, IA | Beverage and Tobacco Product Manufacturing312111 | 20–99 | ◐ LIKELY ACTIVE |
| KWKuhlman Welding and Lake Services, INC. | Spirit Lake, IA | Fabricated Metal Product Manufacturing332312 | — | ◇ UNVERIFIED |
| NINorthern Iowa Die Casting, INC. | Lake Park, IA | Primary Metal Manufacturing331521 | — | ◇ UNVERIFIED |
| ACAlger Companies, Inc. | Milford, IA | Fabricated Metal Product Manufacturing332812 | — | ◇ UNVERIFIED |
| BSBoji Spudz LLC | Arnolds Park, IA | Food Manufacturing311812 | — | ◇ UNVERIFIED |
| FMFerguson Mfg. CO. INC. | Spirit Lake, IA | Primary Metal Manufacturing331221 | — | ◇ UNVERIFIED |
| GLGFrench, LLC | Arnolds Park, IA | Primary Metal Manufacturing331210 | — | ◇ UNVERIFIED |
| JMJackson Millwork - Former Site of | Spirit Lake, IA | Furniture and Related Product Manufacturing337211 | — | ◇ UNVERIFIED |
