| BDBecton Dickinson Sumter | Sumter, SC | Miscellaneous Manufacturing339112 | 500+ | ● ACTIVE |
| CICaterpillar INC Precision Pin Products Group | Sumter, SC | Fabricated Metal Product Manufacturing332721 | 20–99 | ● ACTIVE |
 Bullseye Target Systems LLC | Sumter, SC | Computer and Electronic Product Manufacturing334519 | — | ● ACTIVE |
 Carolina Power Systems of Sumter INC | Sumter, SC | Electrical Equipment, Appliance & Component Manufacturing335313 | — | ● ACTIVE |
 Cmmc Holdings, LLC | Sumter, SC | Fabricated Metal Product Manufacturing332710 | — | ● ACTIVE |
 Palmetto Firearms LLC | Sumter, SC | Fabricated Metal Product Manufacturing332994 | — | ● ACTIVE |
 Peerless Coatings Sc LLC | Sumter, SC | Chemical Manufacturing325510 | — | ● ACTIVE |
 Pilgrim's Pride Protein Conversion | Sumter, SC | Food Manufacturing311613 | 1–19 | ● ACTIVE |
 Singleton Steel, INC. | Sumter, SC | Fabricated Metal Product Manufacturing332312 | — | ● ACTIVE |
| GKGold Kist Sumter Processing Plant | Sumter, SC | Food Manufacturing311613 | — | ◐ LIKELY ACTIVE |
| NMNova Molecular Sumter LLC | Sumter, SC | Chemical Manufacturing325199 | 20–99 | ◐ LIKELY ACTIVE |
| SPSantee Print Works | Sumter, SC | Textile Mills313310 | — | ◐ LIKELY ACTIVE |
| SUSkf USA INC | Sumter, SC | Fabricated Metal Product Manufacturing332991 | — | ◐ LIKELY ACTIVE |
| CICaterpillar INC Hydraulic Cylinder Group Sumter | Sumter, SC | Machinery Manufacturing333120 | — | ◇ UNVERIFIED |
| CSConcrete Supply CO LLC - Shaw Plant | Sumter, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| NRNova Recovery Oz Holdings, LLC | Sumter, SC | Chemical Manufacturing325199 | — | ◇ UNVERIFIED |
| Pilgrim's Pride Feed Mill | Sumter, SC | Food Manufacturing311119 | — | ◇ UNVERIFIED |
| SCSumter Coatings INC | Sumter, SC | Chemical Manufacturing325510 | — | ◇ UNVERIFIED |
 Fire Plus LLC | Sumter, SC | Transportation Equipment Manufacturing336110 | — | ◐ LIKELY ACTIVE |
| ATApex Tool Group - Sumter | Sumter, SC | Primary Metal Manufacturing331512 | 20–99 | ◐ LIKELY ACTIVE |
 Continental Tire the Americas LLC | Sumter, SC | Plastics and Rubber Products Manufacturing326211 | 500+ | ◐ LIKELY ACTIVE |
| FCFlorence Concrete Products, Inc. Sumter Plant | Sumter, SC | Nonmetallic Mineral Product Manufacturing327332 | 20–99 | ◐ LIKELY ACTIVE |
| GRGlasscock Ready Mix Concrete LLC - Central Mix Broad Street | Sumter, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◐ LIKELY ACTIVE |
| IMInterlake Mecalux Sumter | Sumter, SC | Primary Metal Manufacturing331221 | 20–99 | ◐ LIKELY ACTIVE |
| KCKaydon Corporation | Sumter, SC | Fabricated Metal Product Manufacturing332117 | — | ◐ LIKELY ACTIVE |
| KMKrm Midlands LLC - Sumter Plant 14 | Sumter, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◐ LIKELY ACTIVE |
| LCLow Country Pallett & Wood Products INC | Sumter, SC | Wood Product Manufacturing321920 | 20–99 | ◐ LIKELY ACTIVE |
| PPPalmetto Pigeon Plant | Sumter, SC | Food Manufacturing311615 | — | ◐ LIKELY ACTIVE |
| CRC R Jackson Inc-sumter Asphalt Plant | Sumter, SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| GRGlasscock Ready Mix Concrete LLC - Plant 2 Broad Street | Sumter, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◐ LIKELY ACTIVE |
| PTPhibro Tech INC | Sumter, SC | Wood Product Manufacturing321114 | — | ◐ LIKELY ACTIVE |
| AAApac Atlantic INC Sumter Plt #512 | Sumter, SC | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| BBBosch Braking Systems | Sumter, SC | Transportation Equipment Manufacturing336211 | — | ◇ UNVERIFIED |
| BDBurgess Do It Center Sumter | Sumter, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| CFCarolina Furniture Works INC | Sumter, SC | Furniture and Related Product Manufacturing337122 | — | ◇ UNVERIFIED |
| CSConcrete Supply Co., LLC - Georgetown | Sumter, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| CSConcrete Supply CO LLC Sumter Plant | Sumter, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| CHCutler Hammer Incorporated | Sumter, SC | Electrical Equipment, Appliance & Component Manufacturing335313 | — | ◇ UNVERIFIED |
| DODawkins On-site LLC Glasscock Lafayette | Sumter, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| DIDiebold INC | Sumter, SC | Fabricated Metal Product Manufacturing332312 | — | ◇ UNVERIFIED |
| ECEms Chemie (north America) INC | Sumter, SC | Chemical Manufacturing325211 | — | ◇ UNVERIFIED |
| EIEnersys INC | Sumter, SC | Fabricated Metal Product Manufacturing332114 | — | ◇ UNVERIFIED |
| EIEnersys Incorporated | Sumter, SC | Electrical Equipment, Appliance & Component Manufacturing335911 | — | ◇ UNVERIFIED |
| FCFlorence Concrete Products INC Sumter | Sumter, SC | Nonmetallic Mineral Product Manufacturing327332 | — | ◇ UNVERIFIED |
| FFFormed Fiber Technologies, LLC | Sumter, SC | Chemical Manufacturing325222 | — | ◇ UNVERIFIED |
| GRGlasscock Ready Mix Concrete LLC - Divine St Cemco | Sumter, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| MCMetokote Corportation | Sumter, SC | Fabricated Metal Product Manufacturing332812 | — | ◇ UNVERIFIED |
| SPSkf Plant 12b | Sumter, SC | Fabricated Metal Product Manufacturing332991 | — | ◇ UNVERIFIED |
| SCSumter Casket Company | Sumter, SC | Miscellaneous Manufacturing339995 | — | ◇ UNVERIFIED |
| VBVaughan Bassett Furniture-closed | Sumter, SC | Furniture and Related Product Manufacturing337122 | — | ◇ UNVERIFIED |
