 Advanced Radiation Technology & Solutions LLC | Vermillion, SD | Computer and Electronic Product Manufacturing334413 | — | ● ACTIVE |
 Sydell INC. | Burbank, SD | Machinery Manufacturing333111 | — | ● ACTIVE |
| MMMasaba Mining Equipment | Vermillion, SD | Machinery Manufacturing333131 | — | ◐ LIKELY ACTIVE |
| MRMidwest Ready Mix | Vermillion, SD | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| BDBlack Drop Distillery LLC | Wakonda, SD | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| MMMeduvida Meadery LLC | Vermillion, SD | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| S1Still 173, LLC | Vermillion, SD | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| SFStone Faces Distillery | Vermillion, SD | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| VVValiant Vineyards | Vermillion, SD | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BEBasin Electric Power Cooperative - Spirit Mound | Vermillion, SD | Electrical Equipment, Appliance & Component Manufacturing335312 | — | ◇ UNVERIFIED |
| WMWall Medical, Inc. | Vermillion, SD | Miscellaneous Manufacturing339112 | — | ◇ UNVERIFIED |
| XBXIX Brewing Company | Vermillion, SD | Beverage and Tobacco Product Manufacturing312120 | — | ◇ UNVERIFIED |
