| FPForte Power Systems INC | Heflin | Primary Metal Manufacturing | 331318 | — | ◐ LIKELY ACTIVE |
| PCPreferred Compounding CORP | Fruithurst | Plastics and Rubber Products Manufacturing | 326299 | — | ◇ UNVERIFIED |
| TFTyson Foods INC. Heflin Processing Plant | Heflin | Food Manufacturing | 311613 | — | ◇ UNVERIFIED |
| DJDaniel Jackson Meat Processing | Ranburne | Food Manufacturing | 311611 | — | ◐ LIKELY ACTIVE |
| HHeflin | Heflin | Primary Metal Manufacturing | 331318 | 100–499 | ◐ LIKELY ACTIVE |
| HCHigh Country Cellars Winery, INC. | Heflin | Beverage and Tobacco Product Manufacturing | 312130 | — | ◐ LIKELY ACTIVE |
| RPRusken Packaging Heflin | Heflin | Paper Manufacturing | 322211 | 20–99 | ◐ LIKELY ACTIVE |
| TFThe Fruithurst Winery CO. | Fruithurst | Beverage and Tobacco Product Manufacturing | 312130 | — | ◐ LIKELY ACTIVE |
Tree Brand Packaging- AL | Ranburne | Wood Product Manufacturing | 321920 | 100–499 | ◐ LIKELY ACTIVE |
| WCWEBB CONCRETE & BUILDING MATERIALS INC / 204 Industrial Park Drive / Pell City | Heflin | Nonmetallic Mineral Product Manufacturing | 327320 | 20–99 | ◐ LIKELY ACTIVE |
| BEBlazer's Educational Animals | Heflin | Fabricated Metal Product Manufacturing | 332618 | — | ◇ UNVERIFIED |
| FFFruithurst Forest Products, INC. | Fruithurst | Wood Product Manufacturing | 321912 | — | ◇ UNVERIFIED |
| RRRejuvenation Restoration | Heflin | Fabricated Metal Product Manufacturing | 332813 | — | ◇ UNVERIFIED |
| SCSouthwire Company, LLC | Heflin | Primary Metal Manufacturing | 331319 | — | ◇ UNVERIFIED |