| LPLeisure Pools and Spas Manufacturing North America INC | Marion | Plastics and Rubber Products Manufacturing | 326199 | — | ◐ LIKELY ACTIVE |
| BMBoggs Materials INC Mullins Plant | Mullins | Petroleum and Coal Products Manufacturing | 324121 | — | ◐ LIKELY ACTIVE |
| KAKing Asphalt INC - Mullins | Mullins | Petroleum and Coal Products Manufacturing | 324121 | — | ◐ LIKELY ACTIVE |
| NSNew South Marion Plant | Marion | Wood Product Manufacturing | 321911 | — | ◐ LIKELY ACTIVE |
| BMBlumenthal Mills INC | Marion | Textile Mills | 313210 | — | ◇ UNVERIFIED |
| GCGranite Contracting LLC Florence Plant | Latta | Petroleum and Coal Products Manufacturing | 324121 | — | ◇ UNVERIFIED |
| PFPilliod Furniture Incorporated | Nichols | Furniture and Related Product Manufacturing | 337122 | — | ◇ UNVERIFIED |
| RMReady Mixed Concrete #85 Marion | Marion | Nonmetallic Mineral Product Manufacturing | 327320 | — | ◇ UNVERIFIED |
| SISOPAKCO, Inc. | Mullins | — | — | — | ◐ LIKELY ACTIVE |
| SISo-pak-co, INC | Mullins | Food Manufacturing | 311422 | — | ▲ REPORTED CLOSED |
| SPSOPAKCO - Packaging | Mullins | Nonmetallic Mineral Product Manufacturing | 327213 | 100–499 | ◐ LIKELY ACTIVE |
| ALAmerican Light Bulb Mfg INC | Mullins | Electrical Equipment, Appliance & Component Manufacturing | 335110 | — | ◇ UNVERIFIED |
| AIAvm INC | Marion | Primary Metal Manufacturing | 331112 | — | ◇ UNVERIFIED |
| BABgm America INC | Marion | Plastics and Rubber Products Manufacturing | 326199 | — | ◇ UNVERIFIED |
| HSHeritage Sportswear | Marion | Apparel Manufacturing | 315120 | — | ◇ UNVERIFIED |
| IPInternational Paper:sellers-wpc | Sellers | Wood Product Manufacturing | 321219 | — | ◇ UNVERIFIED |
| MCMarion Ceramics, Inc, | Marion | Nonmetallic Mineral Product Manufacturing | 327120 | — | ◇ UNVERIFIED |
| PSPrecision Southeast INC | Marion | Plastics and Rubber Products Manufacturing | 326199 | — | ◇ UNVERIFIED |
| PMPsi Molded Plastics | Marion | Plastics and Rubber Products Manufacturing | 326199 | — | ◇ UNVERIFIED |