| BGBerryville Graphics INC | Berryville | Printing and Related Support Activities | 323117 | 100–499 | ● ACTIVE |
| ITImgen Technologies Lc | Boyce | Computer and Electronic Product Manufacturing | 334516 | — | ● ACTIVE |
| TMTrelleborg Marine Systems Usa, INC. | Berryville | Plastics and Rubber Products Manufacturing | 326150 | — | ◐ LIKELY ACTIVE |
Better Cables LLC | Boyce | Fabricated Metal Product Manufacturing | 332618 | — | ◐ LIKELY ACTIVE |
| CLCochrans Lumber & Millwork, INC. | Berryville | Wood Product Manufacturing | 321918 | — | ◐ LIKELY ACTIVE |
| AWAmerican Woodmark CORP | Berryville | Furniture and Related Product Manufacturing | 337110 | — | ◇ UNVERIFIED |
| SMStuart M Perry INC - Berryville | Berryville | Petroleum and Coal Products Manufacturing | 324121 | — | ◇ UNVERIFIED |
| TMTrelleborg Marine Systems USA INC - Berryville | Berryville | Plastics and Rubber Products Manufacturing | 326199 | — | ◇ UNVERIFIED |
| 5J523 Jack Enders Boulevard | Berryville | Wood Product Manufacturing | 321918 | 20–99 | ◐ LIKELY ACTIVE |
| 6V612 Vineyard | Berryville | Beverage and Tobacco Product Manufacturing | 312130 | — | ◐ LIKELY ACTIVE |
| CHChilly Hollow Brewing Co | Berryville | Beverage and Tobacco Product Manufacturing | 312130 | — | ◐ LIKELY ACTIVE |
| CGCoral Graphics - BV | Berryville | Printing and Related Support Activities | 323117 | 100–499 | ◐ LIKELY ACTIVE |
| HBHollow Brook | Bluemont | Beverage and Tobacco Product Manufacturing | 312130 | — | ◐ LIKELY ACTIVE |
| TOTwin Oaks Tavern Winery | Bluemont | Beverage and Tobacco Product Manufacturing | 312130 | — | ◐ LIKELY ACTIVE |
| TOTwisted Oak Farm Brewery | White Post | Beverage and Tobacco Product Manufacturing | 312130 | — | ◐ LIKELY ACTIVE |
| VVVeramar Vineyard | Berryville | Beverage and Tobacco Product Manufacturing | 312130 | — | ◐ LIKELY ACTIVE |
| WHWild Hare Hard Cider, LLC | Berryville | Beverage and Tobacco Product Manufacturing | 312130 | — | ◐ LIKELY ACTIVE |
| PSP.h.miller Studio, Frame-makers, INC. | Berryville | Miscellaneous Manufacturing | 339999 | — | ◐ LIKELY ACTIVE |
| CIChampion Ironworks Incorporated | Berryville | Fabricated Metal Product Manufacturing | 332312 | — | ◇ UNVERIFIED |
| HOHighland Ornamental Ironworks INC | Berryville | Fabricated Metal Product Manufacturing | 332323 | — | ◇ UNVERIFIED |