| AIAtlantic Industries INC | Frederiksted | Fabricated Metal Product Manufacturing | 332321 | — | ● ACTIVE |
| CVCruzan Viril LTD | Frederiksted | Beverage and Tobacco Product Manufacturing | 312140 | 20–99 | ◐ LIKELY ACTIVE |
| OPOcean Point Terminals (fka Limetree) | Christiansted | Petroleum and Coal Products Manufacturing | 324110 | — | ◐ LIKELY ACTIVE |
| VIVirgin Islands Rum Industries LTD - Cruzan Rum Distillery | Frederiksted | Beverage and Tobacco Product Manufacturing | 312140 | — | ◐ LIKELY ACTIVE |
| DUDiageo Usvi Rum Distillery | Kingshill | Beverage and Tobacco Product Manufacturing | 312140 | — | ◐ LIKELY ACTIVE |
| PHPort Hamilton Refining and Transportation, Lllp | Christiansted | Petroleum and Coal Products Manufacturing | 324110 | — | ◐ LIKELY ACTIVE |
| SCSt Croix Renaissance Group LLP | Kingshill | Primary Metal Manufacturing | 331311 | — | ◇ UNVERIFIED |
| VAVi Asphalt Products CORP | Kingshill | Petroleum and Coal Products Manufacturing | 324121 | — | ◇ UNVERIFIED |
| SCSt. Croix Abattoir | Kingshill | Food Manufacturing | 311611 | — | ◐ LIKELY ACTIVE |
 Heavy Materials Svi - St Croix | Christiansted | Nonmetallic Mineral Product Manufacturing | 327320 | — | ◇ UNVERIFIED |
| RCRemac Concrete LLC Dba Remac Waste Oil | Christiansted | Food Manufacturing | 311225 | — | ◇ UNVERIFIED |
| TBTitan Block | Frederiksted | Nonmetallic Mineral Product Manufacturing | 327331 | — | ◇ UNVERIFIED |
